Research Intelligence

Cardiac Knowledge Graph

Explore cardiac biology through our comprehensive knowledge graph connecting 2M+ biomedical entities including genes, diseases, drugs, and pathways.

2M+
Biomedical Entities
58K
Genes Indexed
8K+
Drug Compounds
1.2M
Publications Linked
Platform

Connected Cardiac Intelligence

Our knowledge graph integrates data from hundreds of sources to create a unified view of cardiac biology, enabling discoveries that would be impossible with siloed data.

Interactive Graph Explorer

Navigate the complex relationships between genes, proteins, diseases, and drugs through our intuitive visual interface. Discover hidden connections, explore pathways, and uncover novel therapeutic targets with real-time graph traversal.

Gene-Disease Associations

Explore curated associations between cardiac genes and cardiovascular diseases, with evidence scores and literature references.

Drug-Target Intelligence

Understand drug mechanisms through comprehensive target profiles including binding affinities, pathway effects, and cardiac safety data.

Expression Data

Tissue-specific profiles

Literature Mining

PubMed integration

Pathway Analysis

KEGG & Reactome

Variant Effects

ClinVar & gnomAD

Data Integration

Unified Biomedical Data

We integrate and harmonize data from the world's leading biomedical databases, creating a comprehensive cardiac-focused knowledge base.

  • Gene Ontology & UniProt

    Comprehensive protein function annotations and sequence data for cardiac proteins

  • OMIM & ClinVar

    Genetic variants associated with inherited cardiomyopathies and arrhythmias

  • DrugBank & ChEMBL

    Drug-target interactions with cardiac safety annotations and binding data

  • GTEx & Human Protein Atlas

    Tissue-specific gene expression profiles across cardiac chambers and cell types

Data Source Statistics
Genes 58,347
Proteins 142,892
Diseases 12,456
Drugs 8,234
Pathways 2,891
Publications 1.2M+
Applications

Research Use Cases

01

Target Discovery

Identify novel drug targets by exploring disease-gene associations and pathway connections in cardiac tissue.

02

Mechanism Understanding

Uncover molecular mechanisms of cardiac diseases through pathway analysis and protein interaction networks.

03

Drug Repurposing

Discover new indications for existing drugs by analyzing shared targets and pathway overlaps.

04

Safety Assessment

Evaluate cardiac safety risks by exploring drug-target interactions with cardiac ion channels and signaling pathways.

05

Literature Review

Accelerate literature searches with AI-powered semantic search across millions of cardiac publications.

Developer

Programmatic API Access

Integrate our knowledge graph into your research workflows with our comprehensive REST and GraphQL APIs.

REST API

Simple RESTful endpoints for entity lookup, relationship queries, and batch operations with JSON responses.

GraphQL

Flexible graph queries for complex traversals. Request exactly the data you need with nested relationships.

Bulk Export

Download subgraphs in standard formats including RDF, Neo4j, and CSV for local analysis.

Authentication

Secure API keys with rate limiting and usage tracking. Enterprise SSO available.

Python SDK

Native Python client with pandas integration for seamless data science workflows.

Documentation

Comprehensive API docs with interactive examples and Jupyter notebooks.

Start Exploring Cardiac Biology

Discover new connections in cardiac research. Access our knowledge graph for free with a research account.

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